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Roche Reports Result of Tecentriq (atezolizumab) + Avastin (bevacizumab) in P-III IMbrave150 Study for Unresectable Hepatocellular Carcinoma

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Roche Reports Result of Tecentriq (atezolizumab) + Avastin (bevacizumab) in P-III IMbrave150 Study for Unresectable Hepatocellular Carcinoma

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  • The P-III IMbrave150 study involve assessing of Tecentriq (1200 mg on day 1 of each 21-day cycle) in combination with Avastin (15 mg/kg on day 1 of each 21-day cycle) vs SoC sorafenib in 501 patients in a ratio (2:1) with unresectable HCC with no prior treatment with systemic therapy
  • The P-III III IMbrave150 study resulted in meeting its co-1EPs demonstrating improvement in OS and PFS- no new safety signals were observed
  • The dual regimen combat multiple cancer indications as Avastin enhances Tecentriq's ability to restore anti-cancer immunity- by inhibiting VEGF related immunosuppression. The results from the study will be submitted to health authorities globally- including the US FDA- EMA & NMPA

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Ref: Roche | Image: Roche


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